Pregame analysis and predictions of the Houston Astros vs. Seattle Mariners MLB game to be played on July 20, 2025 on ESPN.

Paredes suffered a right hamstring injury during Saturday’s matchup with the Seattle Mariners and was removed from the game. Through an interpreter, he said he will return to Houston tomorrow to be evaluated. He said this hamstring injury initially “hurts more than the other one,” which kept him out for three games in June via Matt Kawahara.

The Houston Astros (56-42) and the Seattle Mariners (53-45) wrap up on 3-game series Sunday at T-Mobile Park. First pitch is scheduled for 4:10 p.m. ET. Let's analyze BetMGM Sportsbook's MLB odds around the Astros at Mariners odds and make our expert MLB picks and predictions for the best bets.

BOTTOM LINE: The Seattle Mariners, on a four-game home winning streak, host the Houston Astros. Seattle has a 26-21 record in home games and a 52-45 record overall. The Mariners are 21-8 in games when they did not allow a home run.

Houston is 4-3 against Seattle this season and 3-1 in the last four, but struggled entering the All-Star break. The Astros are 1-5 over the last six games after going on a 6-1 stretch prior to that. Houston is leading the AL West by 5.0 games and has the second-easiest strength of schedule remaining.

Our Astros vs. Mariners predictions expect the pitchers to tell the story this afternoon in what's expected to be a low-scoring affair.

The Mariners opened the second half of the season with a win over Houston on Friday thanks to a tremendous start from Luis Castillo and a couple of big swings.