Israel and Syria have agreed to a ceasefire, the U.S. envoy to Turkey said on Friday, after days of bloodshed in the predominantly Druze area that has killed over 300 people.

The United States said early Saturday that it had negotiated a ceasefire between Israel and Syria's government as new clashes erupted in Syria's Druze heartland following violence that prompted massive Israeli strikes.

Violence in Syria's Druze province has triggered Israeli military action, complicating relations with Turkey and creating a power vacuum that Iran could exploit.

The Israel Defense Forces (IDF) said the Damascus headquarters served as a command center for deploying regime forces to Suwayda, a southern Syrian region gripped by days of deadly clashes between government troops, Druze militias, and Bedouin groups.

Hundreds of people have reportedly fled from Syria into Israel following the outbreak of violence in the south of the country, Israeli media reported on Thursday. The Israeli military returned dozens to the neighbouring country overnight,

Syrian security forces are preparing to redeploy to the Druze-majority Sweida city to quell fighting with Bedouin tribes, a Syrian interior ministry spokesperson said on Friday, further straining a fragile truce in Syria's south.

Syria has accused Israel of attempting to destabilise the country through a series of airstrikes, as tensions escalate in the southern Suweida province. The interim Syrian president has pledged to protect the nation's Druze minority after Israel vowed to target government forces it claims were behind attacks on the religious community.